Action of PKC epsilon in Adipose Tissue Regulates Hepatic Glucose Production

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1081869

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Our previous studies implicated the enzyme protein kinase C epsilon (PKCe) in the development of fat-induced insulin resistance, a key aspect of Type 2 Diabetes. Contrary to expectations we have now shown that animals lacking PKCe only in fat are protected from whole body insulin resistance when fed a high-fat diet. This project will investigate the mechanisms through which PKCe in fat affects insulin action at other tissues, especially liver, to disrupt normal control of blood sugar levels.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $906,859.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Metabolism

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adipose tissue | diabetes | insulin resistance | lipid metabolism | obesity

Related Links