Gastrointestinal mesenchyme supports intestinal stem cells, promotes intestinal regeneration and drives cancer.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1081852

Funding Status
Closed

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Funded Activity Summary

The intestinal lining is continuously renewed by specialised cells called intestinal stem cells. Stem cells throughout the body are regulated by nearby connective tissues. But, the identity of these supportive cells in the gut are unknown. We test whether a discrete population of connective tissue cells in the gut support intestinal stem cells. This project will identify new cellular therapies and targets to promote intestinal repair and manage intestinal cancer.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $548,545.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Physiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

intestinal mucosa | mesenchymal signals | stem cell biology | stem cells | stromal cells

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