delta-containing GABA-A receptors as targets for neuroprotection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1081733

Funding Status
Closed

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Funded Activity Summary

After stroke, the neurotransmitter, GABA spills onto sites located away from the synapse. This spillover is hypothesised to have a protective role in limiting cell death. However the timeframe for this to occur is too long for observing significant beneficial effects after stroke. Therefore, stimulating this naturally occurring protective mechanism early using pharmaceutical interventions that target a specific type of GABAA receptor is an unexplored strategy to minimize cell death after stroke.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $953,825.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

electrophysiology | gamma-aminobutyric acid (GABA) receptors | ligand-gated ion channels | molecular pharmacology | neuroprotection

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