Epigenetic mechanisms of brain dysfunction in psychotic and mood disorders

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1081603

Funding Status
Closed

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Funded Activity Summary

This project investigates the role of epigenetic processes (i.e., functional changes to the genome affecting gene expression) in mediating the long-term effects of childhood trauma in schizophrenia and bipolar-I disorder. We specifically aim to distinguish the effects of trauma-related epigenetic effects on brain structure and function, and on the immune and stress-response systems, and the potential moderation of these effects by structural genetic variants associated with psychosis risk.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $617,836.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Psychiatry (incl. Psychotherapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bioinformatics | brain imaging | epigenetics | gene expression | psychotic disorders

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