Tipping the inflammatory response of TNF in favour of death

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1081272

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Cancer cells promote their own growth by exploiting the body’s natural defence. This natural defence is termed inflammation and cancer cells utilise inflammation to grow and metastasise. We have identified two exciting proteins that are required for cancer cells to stay alive. Under conditions that drive inflammation, if we remove these proteins cancer cells now activate their death signals and die. Our discovery provides new opportunities on fundamental ways by which cancer cells can be killed.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $660,403.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

apoptosis | inflammation | molecular biology | tumour necrosis factor (TNF) | ubiquitination

Related Links