Why do sweetened drinks link to type 2 diabetes?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1081182

Funding Status
Closed

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Funded Activity Summary

Sugars and non-caloric sweeteners are detected in the gut via a common sensor, which may control sugar uptake into the blood. We showed this sensor was defective in type 2 diabetic patients, which could worsen their disease. We will test if high intake of non-caloric sweeteners worsens gut control of blood glucose in healthy volunteers, and if a blocker of this sensor improves control in patients. Deep testing of this sensor will then be used to identify new drugs for managing type 2 diabetes.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $879,411.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G-protein coupled receptors | diabetes mellitus | glucose transporters | glycaemic control | intestinal absorption

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