Interactions between RAGE and the type 1 angiotensin receptor determine the pro-atherosclerotic actions of angiotensin II

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1081013

Funding Status
Closed

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Funded Activity Summary

Heart attacks and strokes are a major cause of death and disability in Australians. Activation of the renin angiotensin system plays a key role in the development and progression of atherosclerosis, the process that leads to narrowing and obstruction of arteries. In preliminary data we have found a way to block these pathways without affecting the control of blood pressure. We believe that interventions based on these data will be important for the prevention and treatment of heart disease.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $521,956.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

angiotensin II | angiotensin receptor | atherosclerosis | receptor binding | renin-angiotensin system (RAS)

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