Using artificial synapses to investigate the functional pathology underlying epilepsy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1080976

Funding Status
Closed

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Funded Activity Summary

Epilepsy is a common neurological disorder. Some forms arise from hereditary mutations to GABA-A receptors. To advance our understanding of epileptogenesis, it is necessary to understand how mutations affect GABA-AR function. We will use a novel ‘artificial synapse’ system to characterise these mutant receptors. This will define how epilepsy is caused and inform us how to best tailor drug treatments for different epilepsy conditions.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $515,256.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

epilepsy | gamma-aminobutyric acid (GABA) receptors | gene mutations | patch clamp | synapse

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