Determining fundamental mechanisms compromised in Kir-linked disease states

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1080682

Funding Status
Closed

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Funded Activity Summary

The human nervous system and organs are reliant on precisely controlled transmission of electrical currents through sodium and potassium channels. Their core functions are compromised when currents fail to switch on and off normally. Faulty potassium channels are implicated in diabetes, epilepsy and heart failure. This project re-examines the mechanisms controlling potassium channels, with a view to scientific and therapeutic discrimination between the different classes present in human cells.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $600,040.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

X-ray crystallography | electrophysiology | ion transport | membrane lipids | potassium channels

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