Investigating a potential new treatment for stroke

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1079400

Funding Status
Closed

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Funded Activity Summary

Blood clots blocking blood flow to the brain (stroke) are a major cause of death and disability. Safety concerns limit approved therapies to a small subset of patients, highlighting an urgent need for safer, more effective drugs. Our studies show that inhibitors of the enzyme PI3Kbeta increase blood clot permeability, increasing clot ‘dissolvability’, without increased bleeding. This raises the possibility that PI3Kbeta inhibitors may represent a safe and effective adjuvant therapy for stroke.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2020

Funding Scheme: Research Fellowships

Funding Amount: $878,522.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

phosphoinositide 3-kinase | platelet adhesion | platelet function | stroke outcome | thrombosis

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