Targeting the interface between tumours and their microenvironment for the treatment of gastrointestinal cancers

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1079257

Funding Status
Closed

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Funded Activity Summary

This fellowship explores the synergistic interactions between intestinal cancer cells and the tumour microenvironment and which promote survival, expansion, migration and invasion as well as facilitating the development of resistance to anti-cancer therapy. Aided by the clinical expertise of my collaborators, my efforts are likely to yield translational outcomes, including the development of therapeutic IL-11 antagonists, and of a serum protein signature indicative of early stage gastric cancer.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2019

Funding Scheme: Research Fellowships

Funding Amount: $785,045.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

gastrointestinal tumourigenesis | inflammatory cytokines | mouse models | signalling pathways | therapeutic target

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