Understanding the basis of autoimmunity in rheumatoid arthritis and type 1 diabetes to underpin the implementation of antigen-specific therapies

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1079238

Funding Status
Closed

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Funded Activity Summary

In autoimmune diseases chronic organ-specific or systemic inflammation has devastating and destructing consequences. In rheumatoid arthritis (RA) and type 1 diabetes (T1D), HLA contribute the major genetic susceptibility. HLA proteins present the antigens which underlie disease development. This proposal underpins my vision for development of antigen-specific therapy in RA and T1D, examining interaction between HLA molecules and antigen and disease, and risk markers for T1D development.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2019

Funding Scheme: Research Fellowships

Funding Amount: $847,490.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Rheumatology and Arthritis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

autoimmunity | biomarkers | pathogenic mechanisms | rheumatoid arthritis | type 1 diabetes mellitus (insulin-dependent diabetes mellitus)

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