Physiological consequences of the loss of inhibin activity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1078879

Funding Status
Closed

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Funded Activity Summary

Inhibin A and B are essential factors in mammalian reproduction, negatively regulating pituitary production of follicle stimulating hormone (FSH). Interestingly, declines in inhibin levels at menopause correlate with a rapid decrease in bone and muscle mass. We propose that inhibin A and B have important physiological roles in the stimulation of bone and muscle growth, and that inhibins could be utilised to treat postmenopausal complications, including osteoporosis and sarcopenia.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $613,035.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Paediatrics and Reproductive Medicine not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

activin and inhibin | bone loss | female menopause | muscle wasting | transforming growth factor beta (TGF-beta)

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