The cell death mechanisms that control regulatory T cell homeostasis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1078763

Funding Status
Closed

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Funded Activity Summary

A central question in immunology is how to prevent destructive immune responses (e.g. autoimmune disease) and initiate productive immune responses (e.g. against cancer). A major breakthrough in this area was the discovery of special immune cells, called a Regulatory T Cells. We propose to discover the genes that determine whether these cells live and die. We will use this information to control appropriate numbers and function of Regulatory T Cells to modify the immune system.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $583,782.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

apoptosis | autoimmunity | homeostasis | regulatory T cells | type 1 diabetes mellitus (insulin-dependent diabetes mellitus)

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