Clarifying the pathogenic role of arousal-hyperventilation in obstructive and central sleep apnoea: Testing fundamental pathophysiological mechanisms and a strategic new treatment

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1078749

Funding Status
Closed

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Funded Activity Summary

This project is designed to understand the mechanisms underpinning much more stable breathing during deep sleep in obstructive sleep apnoea (OSA). A newly developed analytical technique will be used to examine breathing effort changes across sleep, and interactions with respiratory-induced awakenings in OSA patients. In addition, a new treatment designed to stabilise breathing will be tested and refined towards a new treatment option for OSA and for central sleep apnoea.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $414,717.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

arousal | obstructive sleep apnoea | pathophysiology | sleep breathing disorders | upper airway physiology

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