Inhibition of specific NOX isoforms as a new treatment for hypertensive and diabetic retinopathy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1078442

Funding Status
Closed

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Funded Activity Summary

Almost all people with diabetes will develop some retinal disease (diabetic retinopathy, DR) and vision loss. Unfortunately, current treatments target the late stages of DR, do not prevent disease progression and can be damaging. This project will uncover the role of a fundamental process that occurs in DR, called oxidative stress. We will evaluate a major cause of oxidative stress called NOX, which exists in various forms. Animal models of diabetes in which NOXes have been manipulated as well a

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $855,172.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Vision Science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

aldosterone | angiotensin II | diabetic retinopathy | oxidative stress | vascular biology

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