Targeting DNA repair pathways in prostate cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1075970

Funding Status
Closed

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Funded Activity Summary

Understanding the mechanisms in the development of mutations in cancers will assist in development of targeted therapies to overcome chemotherapy resistance. The recently discovered TMPRSS2:ERG fusion in prostate cancer is unique as dominant fusion translocations are uncommon in solid organ malignancy. Activation induced cytidine deaminase (AID) is thought to play a role. Understanding the role of AID and downstream DNA repair pathways may be a target for future therapies in cancer.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Postgraduate Scholarships

Funding Amount: $85,833.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA repair | chemotherapy | gastric cancer | lymphoma | mutagenesis | prostate cancer

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