New ideas in portal hypertension

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1075720

Funding Status
Closed

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Funded Activity Summary

The prevalence of liver cirrhosis worldwide is rising due. The majority of the morbidity and mortality, which arises with cirrhosis, occurs due to the development of portal hypertension. In cirrhosis unexplained vasodilatation of the splanchnic circulation occurs contributing significantly to portal hypertension. I expect to confirm through my experiments that the ACE2/Ang 1-7/Mas axis (alternate RAS) is responsible for this vasodilatation and that antagonists targeting this system may have a role in therapy.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2015

Funding Scheme: Postgraduate Scholarships

Funding Amount: $80,170.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cirrhosis | portal hypertension | renin-angiotensin system (RAS) | therapeutics | vascular reactivity

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