Does statin use have a disease modifying effect in symptomatic knee osteoarthritis?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1074979

Funding Status
Closed

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Funded Activity Summary

Osteoarthritis (OA) is a major cause of knee pain and disability. Treatments are limited to reducing pain and improving function: no therapy slows disease progression, with symptomatic end-stage OA treated by knee replacement. Statins, a drug class used to lower cholesterol levels, may affect the structural progression in knee OA. We propose a randomised controlled trial to see if statin use slows the progression of knee OA, which would delay or prevent the need for joint replacement.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2018

Funding Scheme: Postgraduate Scholarships

Funding Amount: $133,194.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Rheumatology and Arthritis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cartilage | clinical trial | disease progression | knee osteoarthritis | magnetic resonance imaging (MRI) | statins

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