Metabolic homeostasis: a potentially novel regulatory pathway involving caspase-2

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1073771

Funding Status
Closed

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Funded Activity Summary

Altered metabolic regulation contributes to ageing and the development of obesity, type II diabetes and cancer. Recently we discovered that an enzyme, caspase-2, is involved in metabolism, oxidative stress and ageing. We now wish to identify how caspase-2 regulates key metabolic pathways during ageing and nutritional stress. These studies will help to better understand metabolic control and may lead to the discovery of new drug targets to promote healthy ageing and prevent disease.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Early Career Fellowships

Funding Amount: $316,449.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

ageing | biochemistry | caspases | metabolism | stress response

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