The role of diffuse myocardial fibrosis in myocardial stiffness

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1072751

Funding Status
Closed

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Funded Activity Summary

Collagen, a major component of scar, accumulates in some hearts and we may expect this to increase stiffness, threatening heart function. We have shown poor heart relaxation correlates with increased collagen on heart magnetic resonance imaging (MRI). We aim to establish a link between MRI findings and direct measures of heart stiffness, a link between degree of stiffness and amount of collagen and effects of anti-fibrotic therapy on heart collagen; aiding diagnosis, prognosis and outcome.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2019

Funding Scheme: Early Career Fellowships

Funding Amount: $378,032.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

collagen | echocardiography | magnetic resonance imaging (MRI) | myocardial dysfunction | myocardial fibrosis

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