Does mitochondrial metabolism in neurons act to link peripheral metabolic state to motivated food-seeking behaviour?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1072364

Funding Status
Closed

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Funded Activity Summary

Obesity, and its associated pathologies, is a major disease concern. The brain systems that regulate food intake and body weight break down under the strain of obesity and this creates a vicious cycle where failure to regulate metabolism promotes further weight gain. I am investigating how the mitochondrial enzyme CPT1c regulates these brain systems, and whether obesity impairs CPT1c function. Understanding CPT1c function in the brain will help us understand the causes of obesity and diabetes.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2019

Funding Scheme: Early Career Fellowships

Funding Amount: $335,697.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Physiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

behaviour | energy metabolism | glucose homeostasis | hypothalamus | obesity

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