Discovery and development of better pain treatments

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1072113

Funding Status
Closed

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Funded Activity Summary

Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clinical potential.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2019

Funding Scheme: Program Grants

Funding Amount: $9,613,850.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Sensory Systems

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

biochemistry | ion channels | pain | pain mechanisms | pain transmission | peptides | pharmacology | proteomics | structure-function | venom

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