Viral infection and transforming growth factor-beta impair glucocorticoid activity in epithelial cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1072108

Funding Status
Closed

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Funded Activity Summary

Anti-inflammatory types of steroid drugs are commonly used in chronic lung disease including asthma and chronic obstructive pulmonary disease. However, a significant number of sufferers show resistance to the steroid therapy. Our study is developing an understanding of how inflammation limits the anti-inflammatory effects of steroids and we are identifying novel therapeutic targets to improve the effectiveness of treatment of chronic disease.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2018

Funding Scheme: Early Career Fellowships

Funding Amount: $318,299.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-inflammatory | asthma exacerbation | asthma therapy | drugs | glucocorticoids | lung disease | virus

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