Supporting a friend: the role of the molecular scaffold CoREST family in chromatin regulation and neuroprotection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1071250

Funding Status
Closed

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Funded Activity Summary

In diseases such as Alzheimer’s disease, Parkinson’s disease and motor neuron disease, neurons degenerate and die. One contributing factor to neuronal death is inflammation. The aim of this study is to identify mechanisms that protect neurons from death. This project focuses on the role of a family of proteins (CoREST1-3) that function to reverse gene expression changes in inflammation that lead to neurodegeneration.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $354,802.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

chromatin | inflammation | neuroprotection | nitric oxide | transcriptional regulation

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