Long-term metabolic effects of stress and antidepressants: a novel translational animal paradigm of drug-induced obesity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1070935

Funding Status
Closed

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Funded Activity Summary

Do antidepressants contribute to Australia's obesity epidemic? Millions of Australians are treated with antidepressants, which often causes weight gain. Our work shows that even brief exposure to antidepressants exacerbate body weight gain following exposure to chronic stress. This new knowledge represents a significant shift in the understanding of antidepressant-related weight gain. In this project we will study the mechanisms involved in long-term weight gain after exposure to stress and antidepressants in an obesogenic environment.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $518,231.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmacology and Pharmaceutical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antidepressants | behaviour | body composition | body weight regulation | dietary fat | energy intake | major depression | metabolism | obesity | stress

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