Peptide toxins from animal venoms specifically targeting voltage-gated sodium channels as novel analgesics and pesticides

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1070030

Funding Status
Closed

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Funded Activity Summary

This project aims to understand how certain animal toxins that cause analgesic and pesticidal effects in model animals interact with biological ion channels in atomistic detail using computational techniques. By understanding the detailed molecular interactions involved in the binding of the toxins to channels, toxin variants with improved potency and specificity may be designed as promising templates for novel analgesics and pesticides.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Early Career Fellowships

Funding Amount: $316,449.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

biophysics | ion channels | membrane protein | protein binding | protein-protein interaction | toxins

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