The role of Heg-CCM2L signaling in angiogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1069871

Funding Status
Closed

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Funded Activity Summary

Dysfunctional blood vessel growth is an important mechanism of many congenital vascular diseases and other postnatal diseases such as ischemia and cancer. Cerebral cavernous malformations (CCMs) are common vascular disease in brain that cause strokes and seizures in midlife. Due to their location in the brain, CCMs are virtually untreatable, making the development of novel therapies a priority. This proposal aims to understand how the molecular players underlying this brain vascular disease control blood vessel function and growth.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $665,457.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

angiogenesis | blood vessels | cell signalling | cerebrovascular disease | endothelial cells | kinases | knockout mouse | mouse genetics | vascular development

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