Design and evaluation of inhibitors targeting serine proteases in blood to alleviate systemic inflammatory response to coronary artery bypass graft surgery

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1069819

Funding Status
Closed

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Funded Activity Summary

Over 20,000 Australians undergo bypass surgery each year with a 3% mortality rate linked to complications from the procedure. One such common complication is caused by the body’s immune system being activated when the blood comes in contact with the blood bypass pump machine. This project aims to develop new medicines to block this activation of the immune system during bypass surgery to reduce complications and mortality associated with this procedure.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2018

Funding Scheme: Early Career Fellowships

Funding Amount: $317,559.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Bioinformatics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

biochemistry | cardiovascular disease | computational chemistry | drug design | enzyme inhibitors | enzymology

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