Cellular and molecular mechanisms of fungal infection pathogenesis and therapy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1069284

Funding Status
Closed

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Funded Activity Summary

Fungal infections are serious problems for patients with depressed immunity such as chemotherapy or transplant patients. More effective antifungal treatments are needed. We will study a model of fungal infection in zebrafish embryos that recapitulates human penicilliosis. The research will study how the infection establishes and how different types of white blood cells either help or hinder infection establishment. The results will point to new approaches for treating serious fungal infections.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $561,028.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

fungal infection | haematology | leukocytes | macrophages | neutrophils | opportunistic infections | phagocytosis | zebrafish

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