The mechanism of HSV-1 transport in sensory axons and its unique assembly at the axon terminus

Funding Activity

Website
http://grants.uberresearch.com/501100000925/http://purl.org/au-research/grants/nhmrc/1069193/Herpes-simplex-virus-transport-and-assembly-in-nerve-cells

Funding Status
Closed

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Funded Activity Summary

Herpes simplex viruses 1 and 2 cause common diseases such as genital herpes and, occasionally, neonatal deaths and encephalitis and predisposes to HIV infection. New antiviral strategies are required for resistant viruses for control. These aims will be facilitated by understanding how HSV is transported down nerves and across into skin. In this study, we will define how a key viral protein plays a major role in assembly of the virus at the tip of the nerve before it enters skin.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $670,284.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Virology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Herpes simplex virus (HSV) | growth cone | kinesin | neuron | viral proteins | viral replication

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