Role of the miR-200 target Quaking in alternative splicing during EMT and cancer progression

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1068773

Funding Status
Closed

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Funded Activity Summary

The spread of cancer to other organs involves cancer cells changing to a more aggressive state and is a major cause of cancer related death. MicroRNAs are a class of genes that control whether cancer cells become more aggressive by regulating other genes. In this project we will examine the function of a new microRNA target which controls the cancer cell aggression. The outcome will be a better understanding of how cancers spread and the identification of new therapeutic targets.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $443,160.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

alternative splicing | epithelial cells | epithelial-mesenchymal transition (EMT) | gene regulation | microrna

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