The structural resolution of PTEX, the translocon of virulence proteins and malaria parasites.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1068287

Funding Status
Closed

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Funded Activity Summary

The extraordinary virulence of malaria parasites is in part due to their ability to export hundreds of proteins into their red blood cell hosts that help them obtain nutrients and avoid the immune system. Recently we discovered the molecular machine that exports proteins into the host cell and we now wish to establish how it works so drugs can be tailored to block the machine and kill the parasites.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $561,028.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Falciparum malaria | antimalarial | malaria | malaria therapy | protein structure

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