Developing subtype-selective blockers of acid-sensing ion channels for treating peripheral pain

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1067940

Funding Status
Closed

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Funded Activity Summary

Chronic pain is a huge medical problem that affects 1 in 5 adults. There are few drugs available for treating chronic pain, and many of these have limited efficacy and dose-limiting side-effects. Acid-sensing ion channels are proteins that play an essential role in the specialised nerves that sense pain signals. The ultimate goal of this project is to engineer highly selective blockers of these channels that can be used to develop effective analgesics for treating patients with chronic pain.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $641,407.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Proteins and Peptides

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

drug discovery | electrophysiology | ion channels | pain | pain mechanisms | peptides | pharmacokinetics

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