Investigating the therapeutic potential of FTY720 for Human African Trypanosomiasis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1067728

Funding Status
Closed

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Funded Activity Summary

FTY720, is a drug currently used to treat multiple sclerosis, which we have shown is also be able to kill the parasite responsible for African sleeping sickness, Trypanosomes. We aim to identify the target the drug acts on in the parasite to have its affect. Our objective is to improve the activity further by chemical modification to produce a potent, orally available and well characterised, non-toxic drug suitable for preclinical development.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $653,736.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

drug discovery | drug efficacy | mechanism of action | parasitology | therapeutic agents | trypanosomiasis

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