Functional and genomic analysis of the globally disseminated multidrug resistant Escherichia coli ST131 clone

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1067455

Funding Status
Closed

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Funded Activity Summary

Uropathogenic Escherichia coli (UPEC) is a major cause of urinary tract infections (UTI) and sepsis. Recently, a highly virulent clone of UPEC (E. coli ST131) that is resistant to multiple types of antibiotics has emerged and spread worldwide. This project uses genomic and high-throughput functional analysis methods to understand E. coli ST131 virulence and resistance. The outcomes of the work will be a better understanding of how E. coli ST131 causes disease, and potentially new treatment regimes for UTI.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $825,537.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Escherichia coli | antibiotic resistance | bacterial pathogenesis | bacterial virulence factors | functional genomics | urinary tract infection (UTI)

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