(Dys)Regulating junctional tension: a novel mechanism in tumor cell biology

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1067405

Funding Status
Closed

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Funded Activity Summary

This project will study how cancer cells are forced out of their original tissue of origin. This process, called oncogenic extrusion, is important to allow cancer cells to proliferate and invade their surrounding tissue. We have discovered a new cellular mechanism that causes oncogenic extrusion and aim to understand its molecular basis and test how it contributes to breast cancer.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $732,391.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

E-cadherin | actin cytoskeleton | cancer cell biology | cancer metastasis | myosin

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