Understanding how inflammatory bowel disease causes hypersensitivity of colonic sensory nerve endings and increased abdominal pain

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1067335

Funding Status
Closed

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Funded Activity Summary

Patients with inflammatory bowel disease (IBD) commonly experience increased abdominal pain. This project utilises two novel techniques developed by the Chief investigator, that allow us to understand how inflammation of the large intestine leads to increased pain sensations. This project will use these new techniques to identify, for the first time, the sensory nerve endings that detect painful stimuli from within the large intestine; and how these nerve endings become hyperexcitable during inflammation to cause increased abdominal pain.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $589,466.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Sensory Systems

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

colonic motility | intestine | pain transmission | sensory neurons | sensory transduction

Related Links