Neuron to glia signalling: learning how synaptic signalling can promote CNS remyelination

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1066025

Funding Status
Closed

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Funded Activity Summary

An immature cell type in the brain, known as the oligodendrocytes progenitor cell (OPC), receives direct electrical communication from neurons. This communication regulates the behavior of the OPC, affecting its ability to divide and generate new brain cells. This project will identify the signaling molecules that guide the OPC to for this specialized contact with the nerve cell. Understanding this communication has important implications for the treatment of Multiple Sclerosis.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $609,650.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

calcium regulation | calcium signalling | glia-neuron relationship | myelination | oligodendrocytes | remyelination | synapse formation

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