Investigating neuroinflammation and its relationship with progressive brain structural loss in schizophrenia

Funding Activity

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Funded Activity Summary

This project will investigate whether brain inflammation contributes to progressive brain volume loss in people with schizophrenia. Using novel brain scanning we will index whether brain cells involved in inflammation, called microglia, are in an activated state in people with schizophrenia. We expect microglia will be ‘activated’ in a subgroup of patients with schizophrenia, and will be related to progressive brain volume loss in these patients. This information will help us develop new treatments to prevent brain volume loss in the illness.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $466,252.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Psychiatry (incl. Psychotherapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

magnetic resonance imaging (MRI) | microglia | neuroimaging | neuroinflammation | positron emission tomography (PET) | schizophrenia