Studies on the effects of endogenous and exogenous opioids in modulating exercise-induced dyspnoea in people with moderate / severe chronic obstructive pulmonary disease (COPD). Two double-blind randomised, placebo controlled trials.

Funding Activity

Website
http://grants.uberresearch.com/501100000925/http://purl.org/au-research/grants/nhmrc/1065572/A-double-blind-randomised-study-to-explore-the-effect-of-the-bodys-own-morphine-like-chemicals-on-exercise-induced-breathlessness-in-people-with-emphysema

Funding Status
Closed

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Funded Activity Summary

There is evidence that morphine-like chemicals made by the body itself help reduce breathlessness. It is not clear whether this response is because of the effects of these morphine-like chemicals on the brain, in the lung or both. This study will help understand where these chemicals act to reduce breathlessness in people with emphysema during exercise. Subsequently, it will also help to understand whether small, regular doses of morphine safely further reduce breathlessness during exercise.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $197,086.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmacology and Pharmaceutical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

breathlessness | chronic obstructive pulmonary disease (COPD) | dyspnoea | exercise test | opioids