Interactions between host and the gut microbiome in the pathogenesis of ankylosing spondylitis and Crohn's disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1065509

Funding Status
Closed

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Funded Activity Summary

Ankylosing spondylitis (AS) and Crohn's disease (CD) are common immune-mediated diseases affecting primarily the joints of the spine and the gut respectively. Genes play a major role in determining the risk of each disease, and it is likely that those genes cause the disease by interaction with some environmental factor, most likely bacteria residing in the gut. This study aims to test that hypothesis by profiling the bacteria in the gut of patients with the diseases and healthy subjects.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $572,227.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Crohn's disease | enteric bacteria | mucosal immunity | sequencing | spondyloarthropathy

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