PACAP: The mechanism underlying sleep apnoea-induced hypertension

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1065485

Funding Status
Closed

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Funded Activity Summary

10% of Australians suffer from sleep apnoea; a cause of high blood pressure. Untreated, high blood pressure causes heart failure, kidney failure and stroke. A major cause of high blood pressure is an increased amount of nerve activity that controls the heart and blood vessels. In this proposal we will investigate how a brain chemical, called PACAP, affects nerve activity and blood pressure in a model of sleep apnoea. This information may lead to new and better treatments for high blood pressure.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $505,117.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autonomic Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

blood pressure regulation | brainstem | pituitary adenylate cyclase activating peptide (PACAP) | sleep apnoea | sympathetic activity

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