Therapeutic potential of modulating heat shock protein expression for muscle wasting disorder

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1065456

Funding Status
Closed

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Funded Activity Summary

Heat shock proteins help stressed proteins fold back to their original conformation and restore function. In a discovery published in Nature we identified induction of heat shock protein 72 (Hsp72) as a novel approach for muscular dystrophy and other conditions where there is inflammation and muscle weakness. This proposal will investigate whether Hsp72 induction is similarly effective in tackling the muscle wasting and weakness in conditions like ageing and frailty and in muscle injury.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2019

Funding Scheme: Project Grants

Funding Amount: $1,172,146.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Physiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

heat shock proteins | muscle atrophy | muscle regeneration | muscle weakness | muscular dystrophy

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