Targeting mitochondrial metabolism in Diffuse Intrinsic Pontine Gliomas as a novel therapeutic strategy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1065117

Funding Status
Closed

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Funded Activity Summary

Diffuse Intrinsic Pontine Glioma (DIPG) represents the most aggressive cancer of childhood, with no effective treatments available, and almost all children dying within one year of diagnosis. We have successfully grown the first DIPG cells in the laboratory and found a new approach to attack them, by specifically targeting the cell's power source - the mitochondria. We will build on these findings and develop this treatment strategy with the aim to make this novel therapy available to children with this deadly disease.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $607,796.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Therapy (excl. Chemotherapy and Radiation Therapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

brain tumours | brainstem | glioma | mitochondrial function | translational research

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