Novel inhalation formulation of colistin and combination therapy against Gram-negative 'superbugs'

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1065046

Funding Status
Closed

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Funded Activity Summary

Respiratory infections caused by multidrug-resistant Gram-negative bacteria are major health problems for Australians. Colistin is the last-resort defense in most cases. However, parenteral administration of colistin will cause serious side effects. This proposal applies an interdisciplinary approach using aerosol particle engineering, functional lung imaging and antimicrobial pharmacology to develop and characterise novel inhaled powder formulations of colistin and its rational combinations.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $513,896.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmaceutical Sciences

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

aerosol delivery | aerosol transport and deposition | antibiotics | drug delivery systems | inhaler therapy | pharmaceutics | pulmonary infection | respiratory infection | respiratory medicine

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