Structural Studies on Human Glutamic Acid Decarboxylase

Funding Activity

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Funded Activity Summary

Mental health problems are a global issue and are subject to ongoing medical research. We study glutamic acid decarboxylase, a key enzyme responsible for the synthesis of a prominent and abundant neurotransmitter called GABA. GABA is crucial in controlling neuronal responses and facilitating new interconnections between neurones. Lacking GABA is related to epilepsy, Parkinson's disease, and post-traumatic stress. Our study is important for development of new ways to improve the supply of GABA in the brain.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $380,902.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

enzymology | mental health | neurotransmitters | protein conformation | structural biology