IL-10 inhibition of miR-155 in inflammation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1063400

Funding Status
Closed

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Funded Activity Summary

We have identified a microRNA (miRNA) which can elicit the functional outcome of the anti-inflammatory cytokine IL-10. miRNAs constitute a novel mechanism used by cells to regulate gene expression and have shown much promise as a therapeutic tool. Our finding suggests that modulation of miRNAs through the use of miRNA mimics or antisense technology may serve as an alternative and/or synergistic approach for the use of IL-10 as therapy in chronic inflammation.

Funded Activity Details

Start Date: 01-01-2015

End Date: 01-01-2018

Funding Scheme: Project Grants

Funding Amount: $348,818.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

inflammation | interleukins (IL) | microrna | signalling pathways | therapy

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