Do transcription factor-RNA interactions represent a new mechanism of gene regulation?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1063188

Funding Status
Closed

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Funded Activity Summary

The aim of this proposal is to investigate the mechanisms through which genes are switched on and off. We hypothesise that transcription factors, a set of proteins that contacts DNA to regulate genes, can also interact with a separate class of molecules known as RNA. An understanding of how genes are switched on and off is central to devising strategies for fighting many diseases in a rational way. Our work will have implications for biotechnology and gene therapy.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $704,242.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA | RNA binding proteins | gene regulation | protein function | transcription factor

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