Investigation of the functional role of antibodies against myelin proteolipid protein in multiple sclerosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1063170

Funding Status
Closed

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Funded Activity Summary

There is a lot of suggestive evidence that molecules called antibodies might cause a faster progression of disease in people with multiple sclerosis (MS), but this remains to be proven. The proposed study will investigate the mechanisms by which antibodies could hasten MS disease progression. Results of this study will help inform treatment options for people with MS and will also help us to better understand the basic pathogenic mechanisms that can cause MS.

Funded Activity Details

Start Date: 01-01-2014

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $626,174.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibody | axonal injury | demyelinating disease | demyelination | multiple sclerosis (MS) | pathogenic mechanisms | signalling pathways

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